CD180

Across TCGA cell cohorts, CD180 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CD180-associated genes across cancer lineages are BTNL2, C18orf63, and MTRNR2L5. Each is linked with CD180 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD180-to-partner and partner-to-CD180 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BTNL2 grouped by CD180-low versus CD180-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD180→partner) and Y-score (partner→CD180) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	BTNL2 →	+0.034	+4.169	<.001	.008	3	2
BLOOD_Myeloma	C18orf63 →	+0.013	+4.807	<.001	.006	3	1
BLOOD_Myeloma	MTRNR2L5 →	+0.053	+4.807	<.001	.006	3	1
LARGE_INTESTINE	MAGEB4 →	+0.022	+4.415	<.001	.007	3	1
LARGE_INTESTINE	STRA8 →	+0.161	+4.415	<.001	.007	3	1
LARGE_INTESTINE	ZNF804B →	+0.016	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

BTNL2 by CD180 expression — CNS

Explore this box plot interactively →