Across TCGA patient cohorts, CD177 protein abundance is significantly associated with the RNA expression of many other genes, with 8,826 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CD177-associated genes across cancer lineages are AQP9, CSF3R, and FFAR2. Each is linked with CD177 in more than 6 cancer types. Because this analysis shows association rather than direction, both CD177-to-partner and partner-to-CD177 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD177→partner) and Y-score (partner→CD177) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	AQP9 →	+1.051	+0.988	<.001	<.001	3	7
GBM	CSF3R →	+1.084	+1.118	<.001	<.001	3	7
HNSC	FFAR2 →	+0.919	+0.726	.001	.002	3	7
LSCC	FCGR3B →	+1.573	+1.246	<.001	<.001	3	7
LUAD	CXCL8 →	+2.093	+0.908	<.001	<.001	3	7
COAD	CEACAM3 →	+0.827	+0.872	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,826 associations by consensus.

Exploration

CD177 survival (RNA) · tumor vs normal (RNA) · all CD177 data types