Across TCGA patient cohorts, CD177 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD177-associated genes across cancer lineages are JNK2, ATM, and mTOR_pS2448. Each is linked with CD177 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD177-to-partner and partner-to-CD177 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD177→partner) and Y-score (partner→CD177) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.251	+1.906	.001	.016	3	2
UCEC	ATM →	-0.522	-1.906	.004	.016	3	2
SKCM	mTOR_pS2448 →	-0.210	-3.169	.033	.019	3	1
SKCM	4E-BP1_pT70 →	-0.256	-3.000	.009	.035	3	1
UCEC	14-3-3_beta →	-0.099	-1.847	.014	.049	3	1
UCEC	ER-alpha →	-0.655	-1.861	.047	.049	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

CD177 survival (RNA) · tumor vs normal (RNA) · all CD177 data types