CD163

Across TCGA patient cohorts, CD163 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,147 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CD163-associated proteins across cancer lineages are VSIG4, SKAP2, and LCP2. Each is linked with CD163 in more than 9 cancer types. Because this analysis shows association rather than direction, both CD163-to-partner and partner-to-CD163 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD163 versus VSIG4 in GBM, with a Pearson correlation of 0.84.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CD163→partner) and Y-score (partner→CD163) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	VSIG4 →	+1.257	+2.417	<.001	<.001	3	10
GBM	SKAP2 →	+0.862	+2.224	<.001	<.001	3	10
GBM	LCP2 →	+0.614	+2.204	<.001	<.001	3	10
GBM	PARVG →	+0.772	+2.106	<.001	<.001	3	10
OV	DOCK2 →	+0.750	+1.616	<.001	<.001	3	10
GBM	FMNL1 →	+0.755	+2.285	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,147 associations by consensus.

CD163 vs VSIG4 — GBM

Explore this scatter interactively →