CD163

Across TCGA patient cohorts, CD163 protein abundance is significantly associated with the RNA expression of many other genes, with 17,448 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CD163-associated genes across cancer lineages are TLR8, IL21R, and LILRB1. Each is linked with CD163 in more than 9 cancer types. Because this analysis shows association rather than direction, both CD163-to-partner and partner-to-CD163 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD163 versus TLR8 in UCEC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD163→partner) and Y-score (partner→CD163) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TLR8 →	+1.296	+1.004	<.001	<.001	3	10
GBM	IL21R →	+1.216	+1.071	<.001	<.001	3	10
UCEC	LILRB1 →	+1.319	+0.982	<.001	<.001	3	10
GBM	CD33 →	+0.863	+1.210	<.001	<.001	3	10
GBM	JAK3 →	+1.157	+1.065	<.001	<.001	3	10
UCEC	CD4 →	+1.091	+0.797	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,448 associations by consensus.

CD163 vs TLR8 — UCEC

Explore this scatter interactively →