CD163

Across TCGA cell cohorts, CD163 RNA expression is significantly associated with the go_rna of many other GO terms, with 971 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CD163-associated GO terms across cancer lineages are Viral process, Regulation of protein deubiquitination, and Positive regulation of matrix metallopeptidase secretion. Each is linked with CD163 in more than 5 cancer types. Because this analysis shows association rather than direction, both CD163-to-partner and partner-to-CD163 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral process grouped by CD163-low versus CD163-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD163→partner) and Y-score (partner→CD163) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Viral process →	+0.062	+0.132	.001	.009	3	6
STOMACH	Regulation of protein deubiquitination →	+0.111	+0.184	.001	.003	3	5
UPPER_AERODIGESTIVE_TRACT	Positive regulation of matrix metallopeptidase secretion →	-0.185	-0.161	<.001	.001	3	5
SKIN	Regulation of heart rate by chemical signal →	+0.144	+0.116	<.001	.002	3	5
CNS	Regulation of plasma membrane repair →	+0.213	+0.145	<.001	<.001	3	4
CNS	Positive regulation of plasma membrane repair →	+0.117	+0.101	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 971 associations by consensus.

Viral process by CD163 expression — STOMACH

Explore this box plot interactively →