CD160

Across TCGA patient cohorts, CD160 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD160-associated genes across cancer lineages are Akt_pT308, A-Raf_pS299, and GSK-3a-b_pS21_S9. Each is linked with CD160 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD160-to-partner and partner-to-CD160 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Akt_pT308 grouped by CD160-low versus CD160-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD160→partner) and Y-score (partner→CD160) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Akt_pT308 →	+0.748	+2.584	.010	.010	3	2
UCEC	A-Raf_pS299 →	-0.160	-2.459	.004	.019	3	1
UCEC	GSK-3a-b_pS21_S9 →	+0.458	+2.331	.021	.019	3	1
UCEC	Heregulin →	-0.139	-2.584	.015	.011	3	1
UCEC	IGFBP2 →	-0.622	-3.000	.040	.036	3	1
UCEC	p21 →	+0.220	+3.013	.014	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Akt_pT308 by CD160 expression — UCEC

Explore this box plot interactively →