CD160

Across TCGA cell cohorts, CD160 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,478 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CD160-associated GO terms across cancer lineages are Negative regulation of T cell costimulation, Regulation of mRNA splicing, via spliceosome, and Positive regulation of intracellular steroid hormone receptor signaling pathway. Each is linked with CD160 in more than 17 cancer types. Because this analysis shows association rather than direction, both CD160-to-partner and partner-to-CD160 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of T cell costimulation grouped by CD160-low versus CD160-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD160→partner) and Y-score (partner→CD160) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of T cell costimulation →	+0.771	+1.193	<.001	<.001	3	18
BONE	Regulation of mRNA splicing, via spliceosome →	+0.100	+0.434	<.001	<.001	3	16
BREAST	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.159	+0.461	<.001	.009	3	15
STOMACH	Negative regulation of myoblast fusion →	+0.135	+0.638	.006	.008	3	15
BONE	Pre-mRNA catabolic process →	+0.190	+0.314	<.001	<.001	3	15
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.199	+0.464	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,478 associations by consensus.

Negative regulation of T cell costimulation by CD160 expression — BLOOD_Lymphoma

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