CD14

Across TCGA patient cohorts, CD14 mutation is significantly associated with the immune_cell of many other genes, with 8 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CD14-associated genes across cancer lineages are Mast cells, Macrophages, and Melanocytes. Each is linked with CD14 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD14-to-partner and partner-to-CD14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mast cells grouped by CD14-low versus CD14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD14→partner) and Y-score (partner→CD14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Mast cells →	+0.020	+2.212	.013	.034	3	2
COAD	Macrophages →	+0.015	+2.025	.040	.036	3	1
COAD	Melanocytes →	+0.014	+3.093	.020	.016	3	1
COAD	Neutrophils →	+0.014	+2.301	<.001	.019	3	1
STAD	NK cells →	+0.004	+5.597	.004	.040	3	1
BLCA	MPP →	+0.027	+3.194	.037	.048	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Mast cells by CD14 expression — UCEC

Explore this box plot interactively →