CD14

Across TCGA cell cohorts, CD14 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,956 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CD14-associated GO terms across cancer lineages are Response to triacyl bacterial lipopeptide, Cellular response to triacyl bacterial lipopeptide, and Response to diacyl bacterial lipopeptide. Each is linked with CD14 in more than 12 cancer types. Because this analysis shows association rather than direction, both CD14-to-partner and partner-to-CD14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to triacyl bacterial lipopeptide grouped by CD14-low versus CD14-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CD14→partner) and Y-score (partner→CD14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Response to triacyl bacterial lipopeptide →	+1.492	+2.886	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cellular response to triacyl bacterial lipopeptide →	+1.492	+2.886	<.001	<.001	3	13
BREAST	Response to diacyl bacterial lipopeptide →	+1.459	+3.092	<.001	<.001	3	9
BREAST	Cellular response to diacyl bacterial lipopeptide →	+1.459	+3.092	<.001	<.001	3	9
URINARY_TRACT	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.105	+1.155	.007	.005	3	9
BREAST	CD8-positive, alpha-beta T cell activation →	+0.122	+1.509	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,956 associations by consensus.

Response to triacyl bacterial lipopeptide by CD14 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →