CD101

Across TCGA patient cohorts, CD101 mutation is significantly associated with the RNA expression of many other genes, with 2,621 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD101-associated genes across cancer lineages are ICMT, NUSAP1, and KNL1. Each is linked with CD101 in more than 2 cancer types. Because this analysis shows association rather than direction, both CD101-to-partner and partner-to-CD101 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ICMT grouped by CD101-low versus CD101-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD101→partner) and Y-score (partner→CD101) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ICMT →	+0.343	+2.233	.002	.001	3	3
UCEC	NUSAP1 →	+0.553	+2.202	.004	.001	3	3
UCEC	KNL1 →	+0.556	+2.329	<.001	<.001	3	3
UCEC	PPP2R2D →	+0.231	+2.565	.004	<.001	3	3
UCEC	HASPIN →	+0.703	+2.108	<.001	.002	3	3
UCEC	E2F2 →	+0.541	+2.807	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,621 associations by consensus.

ICMT by CD101 expression — UCEC

Explore this box plot interactively →