CD101

Across TCGA patient cohorts, CD101 mutation is significantly associated with the total protein of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD101-associated genes across cancer lineages are JNK2, p21, and ASNS. Each is linked with CD101 in more than 2 cancer types. Because this analysis shows association rather than direction, both CD101-to-partner and partner-to-CD101 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK2 grouped by CD101-low versus CD101-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD101→partner) and Y-score (partner→CD101) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.188	+1.459	.003	.012	3	3
COAD	p21 →	+0.241	+2.849	.045	.034	3	2
COAD	ASNS →	+0.893	+2.815	<.001	.036	3	2
UCEC	ACC1 →	+0.235	+2.013	.046	.016	3	2
UCEC	INPP4B →	-0.239	-2.415	.022	.002	3	2
UCEC	mTOR_pS2448 →	-0.145	-1.980	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

JNK2 by CD101 expression — UCEC

Explore this box plot interactively →