CCZ1B

Across TCGA patient cohorts, CCZ1B mutation is significantly associated with the RNA expression of many other genes, with 3,294 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCZ1B-associated genes across cancer lineages are OR2B3, LINC02559, and KRTAP20-3. Each is linked with CCZ1B in more than 1 cancer types. Because this analysis shows association rather than direction, both CCZ1B-to-partner and partner-to-CCZ1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2B3 grouped by CCZ1B-low versus CCZ1B-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCZ1B→partner) and Y-score (partner→CCZ1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	OR2B3 →	+0.165	+5.653	<.001	.003	3	2
CESC	LINC02559 →	+1.376	+6.342	<.001	.001	3	2
UCEC	KRTAP20-3 →	+0.079	+4.397	<.001	<.001	3	2
UCEC	MIR188 →	+0.138	+3.412	.007	<.001	3	2
UCEC	RNA5SP407 →	+0.202	+2.682	<.001	.004	3	2
UCEC	RNA5SP417 →	+0.701	+2.821	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,294 associations by consensus.

OR2B3 by CCZ1B expression — READ

Explore this box plot interactively →