CCZ1B

Across TCGA cell cohorts, CCZ1B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,456 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCZ1B-associated GO terms across cancer lineages are Response to dehydroepiandrosterone, Negative regulation of mRNA splicing, via spliceosome, and U2-type prespliceosome assembly. Each is linked with CCZ1B in more than 11 cancer types. Because this analysis shows association rather than direction, both CCZ1B-to-partner and partner-to-CCZ1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to dehydroepiandrosterone grouped by CCZ1B-low versus CCZ1B-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCZ1B→partner) and Y-score (partner→CCZ1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Response to dehydroepiandrosterone →	+0.202	+0.977	<.001	.003	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mRNA splicing, via spliceosome →	+0.106	+1.080	.002	.005	3	12
SOFT_TISSUE	U2-type prespliceosome assembly →	+0.074	+0.776	.003	.002	3	12
BONE	Negative regulation of RNA splicing →	+0.135	+0.962	<.001	<.001	3	11
BLOOD_Lymphoma	Positive regulation of isotype switching to IgG isotypes →	+0.113	+0.909	.001	<.001	2	12
BONE	Nucleic acid transport →	+0.102	+0.868	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,456 associations by consensus.

Response to dehydroepiandrosterone by CCZ1B expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →