CCT8L1P

Across TCGA pan-cancer cohorts, CCT8L1P RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated CCT8L1P data layer compared with 1 for mass-spec protein.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher CCT8L1P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCT8L1P expression acts as an unfavorable survival marker, although some lineages such as BLCA and UCS show a favorable association.

READ, BLCA, and COAD are the cancer types where CCT8L1P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Tertile	II,III,IV	0.174	0.751	<.001	57	view →
BLCA	OS	Median	II,III,IV	0.514	0.371	.011	49	view →
COAD	OS	Tertile	All	0.642	0.844	<.001	42	view →
ACC	OS	Tertile	All	0.634	0.965	.002	31	view →
UCS	DFS	Median	IV	0.952	0.367	.001	24	view →
LUAD	DFS	Tertile	IV	0.450	0.900	.015	22	view →
PAAD	DFS	Tertile	All	0.622	0.386	.002	18	view →
LGG	DFS	Median	All	0.672	0.789	.001	17	view →
ESCA	OS	Quartile	III,IV	0.820	0.313	.005	16	view →
OV	DFS	Median	All	0.419	0.343	.026	14	view →
MESO	OS	Median	IV	0.863	0.397	.007	14	view →
PRAD	OS	Quartile	All	0.703	0.902	.003	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

CCT8L1P–READ (DFS)

Open the READ breakdown →