CCT8

Across TCGA patient cohorts, CCT8 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,319 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCT8-associated proteins across cancer lineages are GART, USP16, and SON. Each is linked with CCT8 in more than 7 cancer types. Because this analysis shows association rather than direction, both CCT8-to-partner and partner-to-CCT8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCT8 versus GART in UCEC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCT8→partner) and Y-score (partner→CCT8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GART →	+0.433	+0.824	<.001	<.001	3	8
OV	USP16 →	+0.222	+0.502	<.001	<.001	3	7
GBM	SON →	+0.264	+0.306	<.001	<.001	3	7
GBM	MCM3 →	+0.718	+0.282	.001	.001	3	7
GBM	MCM6 →	+0.762	+0.313	<.001	<.001	3	7
BRCA	RRP1B_S513 →	+1.261	+0.538	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,319 associations by consensus.

CCT8 vs GART — UCEC

Explore this scatter interactively →