CCT6P3

Across TCGA patient cohorts, CCT6P3 mutation is significantly associated with the RNA expression of many other genes, with 67 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CCT6P3-associated genes across cancer lineages are RNU4-75P, LINC01327, and LINC02536. Each is linked with CCT6P3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCT6P3-to-partner and partner-to-CCT6P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-75P grouped by CCT6P3-low versus CCT6P3-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCT6P3→partner) and Y-score (partner→CCT6P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU4-75P →	+0.297	+6.936	<.001	<.001	3	2
HNSC	LINC01327 →	+0.086	+6.008	.003	.002	3	2
HNSC	LINC02536 →	+0.109	+5.368	<.001	.005	3	1
HNSC	KRTAP4-3 →	+0.071	+6.763	<.001	<.001	3	1
HNSC	RNU105C →	+0.294	+5.578	<.001	.004	3	1
HNSC	RNA5SP46 →	+0.332	+5.736	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 67 associations by consensus.

RNU4-75P by CCT6P3 expression — HNSC

Explore this box plot interactively →