Across TCGA pan-cancer cohorts, CCT6P1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of CCT6P1’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CCT6P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCT6P1 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.
HNSC, COAD, and KIRC are the cancer types where CCT6P1 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCT6P1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.