CCT6B

Across TCGA pan-cancer cohorts, CCT6B mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CCT6B data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CCT6B mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CCT6B expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LSCC show a favorable association.

CCRCC, LSCC, and LUAD are the cancer types where CCT6B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	1.000	0.491	.009	39	view →
LSCC	DFS	Median	All	0.848	0.580	.005	10	view →
LUAD	OS	Median	III,IV	0.174	0.801	.038	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CCT6B–CCRCC (OS)

Open the CCRCC breakdown →