CCT6B

Across TCGA patient cohorts, CCT6B protein abundance is significantly associated with the RNA expression of many other genes, with 17,672 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCT6B-associated genes across cancer lineages are SERINC1, C11orf1, and AK7. Each is linked with CCT6B in more than 1 cancer types. Because this analysis shows association rather than direction, both CCT6B-to-partner and partner-to-CCT6B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCT6B versus SERINC1 in BRCA, with a Pearson correlation of 0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCT6B→partner) and Y-score (partner→CCT6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SERINC1 →	+0.636	+0.499	<.001	<.001	3	2
BRCA	C11orf1 →	+0.830	+0.669	<.001	<.001	3	2
BRCA	AK7 →	+0.709	+0.631	.001	.001	3	2
BRCA	FBXO15 →	+0.789	+0.684	<.001	<.001	3	2
CCRCC	ESAM →	+0.702	+0.297	.003	.001	3	2
BRCA	NUBPL →	+0.483	+0.430	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,672 associations by consensus.

CCT6B vs SERINC1 — BRCA

Explore this scatter interactively →