CCT6A

Across TCGA patient cohorts, CCT6A protein abundance is significantly associated with the RNA expression of many other genes, with 14,270 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCT6A-associated genes across cancer lineages are TCP1, MRPL18, and RBMS3. Each is linked with CCT6A in more than 6 cancer types. Because this analysis shows association rather than direction, both CCT6A-to-partner and partner-to-CCT6A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCT6A versus TCP1 in BRCA, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCT6A→partner) and Y-score (partner→CCT6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TCP1 →	+0.531	+0.223	<.001	<.001	3	7
UCEC	MRPL18 →	+0.626	+0.197	<.001	.002	3	6
UCEC	RBMS3 →	-0.621	-0.213	<.001	<.001	3	6
HNSC	RASGRP4 →	-0.466	-0.254	.003	.003	3	6
OV	PODN →	-1.060	-0.270	.001	<.001	3	6
LSCC	ACAT2 →	+0.873	+0.254	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,270 associations by consensus.

CCT6A vs TCP1 — BRCA

Explore this scatter interactively →