CCT5

Across TCGA patient cohorts, CCT5 protein abundance is significantly associated with the RNA expression of many other genes, with 14,350 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCT5-associated genes across cancer lineages are TCP1, MRPL18, and ACAT2. Each is linked with CCT5 in more than 6 cancer types. Because this analysis shows association rather than direction, both CCT5-to-partner and partner-to-CCT5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCT5 versus TCP1 in UCEC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCT5→partner) and Y-score (partner→CCT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TCP1 →	+0.744	+0.272	<.001	<.001	3	7
UCEC	MRPL18 →	+0.932	+0.278	<.001	<.001	3	6
LSCC	ACAT2 →	+0.978	+0.229	<.001	<.001	3	6
COAD	SPARCL1 →	-1.378	-0.232	<.001	<.001	3	6
LSCC	GTF3C6 →	+0.584	+0.227	<.001	<.001	3	6
BRCA	HDDC2 →	+0.405	+0.167	.003	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,350 associations by consensus.

CCT5 vs TCP1 — UCEC

Explore this scatter interactively →