CCT3

Across TCGA patient cohorts, CCT3 protein abundance is significantly associated with the RNA expression of many other genes, with 14,166 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCT3-associated genes across cancer lineages are TCP1, RPF2, and MRPL18. Each is linked with CCT3 in more than 7 cancer types. Because this analysis shows association rather than direction, both CCT3-to-partner and partner-to-CCT3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCT3 versus TCP1 in OV, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCT3→partner) and Y-score (partner→CCT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TCP1 →	+0.616	+0.261	.001	.004	3	8
GBM	RPF2 →	+0.460	+0.169	<.001	<.001	3	8
UCEC	MRPL18 →	+0.752	+0.255	<.001	<.001	3	7
OV	LHFPL6 →	-1.026	-0.187	<.001	.001	3	7
UCEC	GTF3C6 →	+0.693	+0.282	<.001	<.001	3	7
OV	MTFR2 →	+0.715	+0.190	.003	.008	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,166 associations by consensus.

CCT3 vs TCP1 — OV

Explore this scatter interactively →