CCT2

Across TCGA patient cohorts, CCT2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,352 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCT2-associated genes across cancer lineages are TCP1, GTF3C6, and MRPL18. Each is linked with CCT2 in more than 7 cancer types. Because this analysis shows association rather than direction, both CCT2-to-partner and partner-to-CCT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCT2 versus TCP1 in OV, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCT2→partner) and Y-score (partner→CCT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TCP1 →	+0.688	+0.300	<.001	.001	3	8
UCEC	GTF3C6 →	+0.680	+0.169	<.001	<.001	3	8
UCEC	MRPL18 →	+0.610	+0.163	<.001	<.001	3	6
OV	ACAT2 →	+0.868	+0.306	<.001	<.001	3	6
GBM	RPF2 →	+0.467	+0.233	<.001	.001	3	6
GBM	HDAC2 →	+0.724	+0.214	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,352 associations by consensus.

CCT2 vs TCP1 — OV

Explore this scatter interactively →