CCSER2

Across TCGA patient cohorts, CCSER2 mutation is significantly associated with the RNA expression of many other genes, with 3,819 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCSER2-associated genes across cancer lineages are RNA5SP393, PCNT, and MVD. Each is linked with CCSER2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCSER2-to-partner and partner-to-CCSER2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP393 grouped by CCSER2-low versus CCSER2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCSER2→partner) and Y-score (partner→CCSER2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP393 →	+0.446	+4.341	.001	.003	3	2
UCEC	PCNT →	+0.345	+1.643	.005	.003	3	2
UCEC	MVD →	+0.538	+2.556	<.001	<.001	3	2
UCEC	ZNF57 →	+0.390	+2.917	<.001	<.001	3	2
UCEC	B3GNT4 →	+0.414	+2.180	<.001	<.001	3	2
UCEC	CDH1 →	+0.754	+1.946	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,819 associations by consensus.

RNA5SP393 by CCSER2 expression — BRCA

Explore this box plot interactively →