CCSER2

Across TCGA cell cohorts, CCSER2 mutation is significantly associated with the RNA expression of many other genes, with 50 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCSER2-associated genes across cancer lineages are PRM2, TSHB, and LRIT1. Each is linked with CCSER2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCSER2-to-partner and partner-to-CCSER2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRM2 grouped by CCSER2-low versus CCSER2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCSER2→partner) and Y-score (partner→CCSER2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PRM2 →	+0.027	+3.969	<.001	.009	3	1
BLOOD_Leukemia	TSHB →	+0.176	+3.691	<.001	.002	3	1
BLOOD_Leukemia	LRIT1 →	+0.036	+3.684	<.001	.004	3	1
BLOOD_Leukemia	HTR5A →	+0.032	+3.824	<.001	.001	3	1
BLOOD_Leukemia	CRYGC →	+0.029	+3.969	<.001	.009	3	1
BLOOD_Leukemia	CDH16 →	+0.031	+4.442	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

PRM2 by CCSER2 expression — BLOOD_Leukemia

Explore this box plot interactively →