CCSAP

Across TCGA pan-cancer cohorts, CCSAP mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CCSAP data layer compared with 20 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CCSAP mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CCSAP expression acts as an unfavorable survival marker, although some lineages such as LUAD and GBM show a favorable association.

LUAD, UCEC, and GBM are the cancer types where CCSAP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	1.000	0.365	.006	18	view →
UCEC	OS	Tertile	II,III,IV	0.329	1.000	.003	16	view →
GBM	DFS	Median	All	0.825	0.671	.039	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CCSAP–LUAD (OS)

Open the LUAD breakdown →