CCRL2

Across TCGA cell cohorts, CCRL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,480 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCRL2-associated GO terms across cancer lineages are Plasminogen activation, Regulation of lysosomal membrane permeability, and Regulation of receptor binding. Each is linked with CCRL2 in more than 9 cancer types. Because this analysis shows association rather than direction, both CCRL2-to-partner and partner-to-CCRL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Plasminogen activation grouped by CCRL2-low versus CCRL2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCRL2→partner) and Y-score (partner→CCRL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Plasminogen activation →	+0.314	+0.991	.001	.002	3	10
PANCREAS	Regulation of lysosomal membrane permeability →	-0.173	-1.816	.001	<.001	3	9
LUNG_NSCLC_LUSC	Regulation of receptor binding →	-0.337	-1.404	<.001	<.001	3	9
STOMACH	Regulation of potassium ion transmembrane transport →	+0.184	+1.981	<.001	<.001	3	9
STOMACH	Regulation of potassium ion transport →	+0.172	+1.829	<.001	.001	3	9
OVARY	Positive regulation of transmission of nerve impulse →	+1.366	+1.160	<.001	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,480 associations by consensus.

Plasminogen activation by CCRL2 expression — OESOPHAGUS

Explore this box plot interactively →