CCRL2

Across TCGA cell cohorts, CCRL2 mutation is significantly associated with the mutation status of many other genes, with 2,788 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCRL2-associated genes across cancer lineages are CCR2, GHSR, and PDS5A. Each is linked with CCRL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCRL2-to-partner and partner-to-CCRL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCR2 grouped by CCRL2-low versus CCRL2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCRL2→partner) and Y-score (partner→CCRL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CCR2 →	+4.560	+4.870	<.001	<.001	1	1
BLOOD_Leukemia	GHSR →	+4.560	+4.870	<.001	<.001	1	1
BLOOD_Leukemia	PDS5A →	+3.560	+4.247	.002	.002	1	1
BLOOD_Leukemia	CLCC1 →	+4.560	+4.309	.007	.007	1	1
BLOOD_Leukemia	FLT3 →	+2.975	+4.741	<.001	<.001	1	1
BLOOD_Leukemia	MRPS2 →	+4.560	+4.309	.007	.007	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,788 associations by consensus.

CCR2 by CCRL2 expression — BLOOD_Leukemia

Explore this box plot interactively →