CCR8

Across TCGA pan-cancer cohorts, CCR8 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CCR8 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CCR8 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CCR8 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

COAD, HNSC, and LIHC are the cancer types where CCR8 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.321	0.875	<.001	48	view →
HNSC	OS	Median	III,IV	0.181	0.746	.001	24	view →
LIHC	DFS	Median	All	0.094	0.555	.002	12	view →
UCEC	DFS	Median	II,III,IV	1.000	0.445	.043	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CCR8–COAD (OS)

Open the COAD breakdown →