CCR8

Across TCGA patient cohorts, CCR8 mutation is significantly associated with the RNA expression of many other genes, with 2,365 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCR8-associated genes across cancer lineages are TAF9, FRG1HP, and TEX30. Each is linked with CCR8 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCR8-to-partner and partner-to-CCR8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAF9 grouped by CCR8-low versus CCR8-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCR8→partner) and Y-score (partner→CCR8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TAF9 →	+0.754	+3.087	<.001	<.001	3	2
UCEC	FRG1HP →	+0.667	+3.119	<.001	<.001	3	2
SKCM	TEX30 →	+0.687	+2.594	.002	.006	3	2
UCEC	SLC25A4 →	+0.578	+2.724	.001	.003	3	2
UCEC	GUF1 →	+0.458	+3.609	.001	.001	3	2
UCEC	PCGF6 →	+0.507	+3.483	.005	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,365 associations by consensus.

TAF9 by CCR8 expression — UCEC

Explore this box plot interactively →