CCR8

Across TCGA cell cohorts, CCR8 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,229 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCR8-associated GO terms across cancer lineages are Angiogenesis, Regulation of vitamin metabolic process, and Negative regulation of cardiac muscle adaptation. Each is linked with CCR8 in more than 4 cancer types. Because this analysis shows association rather than direction, both CCR8-to-partner and partner-to-CCR8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Angiogenesis grouped by CCR8-low versus CCR8-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCR8→partner) and Y-score (partner→CCR8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Angiogenesis →	-0.057	-0.010	.006	.002	3	5
CNS	Regulation of vitamin metabolic process →	-0.108	-0.010	.005	.004	3	5
CNS	Negative regulation of cardiac muscle adaptation →	-0.140	-0.009	.009	.009	3	4
CNS	Negative regulation of cardiac muscle hypertrophy in response to stress →	-0.140	-0.009	.009	.009	3	4
BLOOD_Leukemia	Lipoprotein localization →	+0.095	+1.478	<.001	<.001	3	4
CNS	Membrane repolarization during action potential →	-0.158	-0.014	.002	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,229 associations by consensus.

Angiogenesis by CCR8 expression — CNS

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