CCR8

Across TCGA cell cohorts, CCR8 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCR8-associated genes across cancer lineages are IQCF5 and FABP12. Each is linked with CCR8 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCR8-to-partner and partner-to-CCR8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IQCF5 grouped by CCR8-low versus CCR8-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCR8→partner) and Y-score (partner→CCR8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IQCF5 →	+0.121	+5.201	<.001	.006	3	1
CNS	FABP12 →	+0.189	+4.981	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

IQCF5 by CCR8 expression — BLOOD_Leukemia

Explore this box plot interactively →