CCR7

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCR7 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,018 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCR7-associated proteins across cancer lineages are WAS, WDFY4, and WIPF1. Each is linked with CCR7 in more than 9 cancer types. Because this analysis shows association rather than direction, both CCR7-to-partner and partner-to-CCR7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCR7 versus WAS in GBM, with a Pearson correlation of 0.72.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCR7→partner) and Y-score (partner→CCR7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMWAS →+0.666+0.728<.001<.001310
HNSCWDFY4 →+0.594+1.040<.001<.001310
UCECWIPF1 →+0.640+0.932<.001.001310
BRCAZAP70 →+0.836+1.275<.001<.001310
HNSCSAMHD1 →+0.630+1.082<.001<.001310
GBMSEPTIN1 →+1.301+0.906<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 21,018 associations by consensus.

CCR7 vs WAS — GBM

Per-sample scatter of CCR7 vs WAS in GBM (Pearson r = 0.72).

Explore this scatter interactively →

Exploration