CCR7

Across TCGA patient cohorts, CCR7 mutation is significantly associated with the RNA expression of many other genes, with 1,170 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCR7-associated genes across cancer lineages are LINC01974, RNA5SP321, and TRAJ29. Each is linked with CCR7 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCR7-to-partner and partner-to-CCR7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01974 grouped by CCR7-low versus CCR7-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCR7→partner) and Y-score (partner→CCR7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	LINC01974 →	+0.163	+6.305	<.001	.001	3	2
CESC	RNA5SP321 →	+0.319	+5.539	<.001	.004	3	2
CESC	TRAJ29 →	+0.509	+5.010	<.001	.009	3	2
LIHC	KRTAP22-2 →	+0.386	+5.878	<.001	.002	3	2
LIHC	LINC01072 →	+0.129	+6.305	<.001	.001	3	2
BRCA	CCDC137P →	+0.065	+4.635	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,170 associations by consensus.

LINC01974 by CCR7 expression — LIHC

Explore this box plot interactively →