CCR6

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCR6 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,425 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCR6-associated proteins across cancer lineages are CORO1A, EVL, and FYB1. Each is linked with CCR6 in more than 6 cancer types. Because this analysis shows association rather than direction, both CCR6-to-partner and partner-to-CCR6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCR6 versus CORO1A in LSCC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCR6→partner) and Y-score (partner→CCR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCCORO1A →+0.535+0.234<.001<.00137
HNSCEVL →+0.686+0.374<.001<.00137
HNSCFYB1 →+0.657+0.402<.001<.00137
HNSCGRAP2 →+0.852+0.473<.001<.00137
LSCCLPXN →+0.534+0.225<.001<.00137
HNSCNFATC2_S236 →+1.008+0.357<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,425 associations by consensus.

CCR6 vs CORO1A — LSCC

Per-sample scatter of CCR6 vs CORO1A in LSCC (Pearson r = 0.62).

Explore this scatter interactively →

Exploration