CCR6

Across TCGA cell cohorts, CCR6 RNA expression is significantly associated with the go_rna of many other GO terms, with 886 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible CCR6-associated GO terms across cancer lineages are Positive regulation of flagellated sperm motility involved in capacitation, Regulation of protein localization to early endosome, and Positive regulation of protein localization to early endosome. Each is linked with CCR6 in more than 4 cancer types. Because this analysis shows association rather than direction, both CCR6-to-partner and partner-to-CCR6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of flagellated sperm motility involved in capacitation grouped by CCR6-low versus CCR6-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCR6→partner) and Y-score (partner→CCR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Positive regulation of flagellated sperm motility involved in capacitation →	+0.501	+0.927	<.001	<.001	3	5
BREAST	Regulation of protein localization to early endosome →	-0.099	-0.053	.003	.008	3	4
BREAST	Positive regulation of protein localization to early endosome →	-0.099	-0.053	.003	.008	3	4
BREAST	Positive regulation of leukocyte chemotaxis →	-0.104	-0.085	.001	.007	3	4
BREAST	Positive regulation of chemotaxis →	-0.097	-0.067	<.001	<.001	3	4
BREAST	Atrial cardiac muscle cell differentiation →	-0.927	-0.092	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 886 associations by consensus.

Positive regulation of flagellated sperm motility involved in capacitation by CCR6 expression — BLOOD_Lymphoma

Explore this box plot interactively →