CCR5

Across TCGA patient cohorts, CCR5 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,102 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCR5-associated proteins across cancer lineages are RCSD1, RCSD1_S351, and SAMSN1_S23. Each is linked with CCR5 in more than 9 cancer types. Because this analysis shows association rather than direction, both CCR5-to-partner and partner-to-CCR5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCR5 versus RCSD1 in HNSC, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCR5→partner) and Y-score (partner→CCR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RCSD1 →	+0.689	+1.227	<.001	<.001	3	10
BRCA	RCSD1_S351 →	+0.825	+1.284	<.001	<.001	3	10
BRCA	SAMSN1_S23 →	+0.976	+1.195	<.001	<.001	3	10
GBM	SASH3 →	+0.622	+1.247	<.001	<.001	3	10
GBM	SEPTIN1 →	+1.232	+1.239	<.001	<.001	3	10
GBM	SKAP2 →	+0.828	+1.190	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,102 associations by consensus.

CCR5 vs RCSD1 — HNSC

Explore this scatter interactively →