Across TCGA cell cohorts, CCR4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,236 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCR4-associated GO terms across cancer lineages are Cellular component disassembly, Response to chemokine, and Cellular response to chemokine. Each is linked with CCR4 in more than 5 cancer types. Because this analysis shows association rather than direction, both CCR4-to-partner and partner-to-CCR4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCR4→partner) and Y-score (partner→CCR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Cellular component disassembly →	+0.021	+1.232	.002	.006	3	6
BREAST	Response to chemokine →	-0.075	-0.043	.002	.002	3	6
BREAST	Cellular response to chemokine →	-0.075	-0.043	.002	.002	3	6
LARGE_INTESTINE	Spliceosomal snRNP assembly →	+0.070	+0.055	<.001	.008	3	6
LARGE_INTESTINE	Establishment of RNA localization →	+0.053	+0.060	.005	.002	3	6
BREAST	Regulation of DNA-templated transcription elongation →	+0.054	+0.046	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,236 associations by consensus.

Exploration

CCR4 survival (RNA) · tumor vs normal (RNA) · all CCR4 data types