Across TCGA patient cohorts, CCR3 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCR3-associated genes across cancer lineages are ERK2, Fibronectin, and JNK2. Each is linked with CCR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCR3-to-partner and partner-to-CCR3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCR3→partner) and Y-score (partner→CCR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.219	+2.000	.011	.032	3	1
UCEC	Fibronectin →	-0.346	-2.312	.019	.034	3	1
UCEC	JNK2 →	+0.324	+3.026	<.001	.018	3	1
UCEC	N-Ras →	-0.115	-1.986	.032	.032	3	1
UCEC	p21 →	+0.259	+2.700	.002	.006	3	1
UCEC	p62 Lck ligand →	+0.382	+3.331	.009	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

CCR3 survival (RNA) · tumor vs normal (RNA) · all CCR3 data types