Across TCGA pan-cancer cohorts, CCR12P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of CCR12P’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where CCR12P RNA is repressed in tumor relative to normal tissue. In most cancer types CCR12P is over-expressed in tumor, although a few such as COAD and THCA show the opposite, repressed pattern.
COAD and THCA are the cancer types where CCR12P tumor–normal differential expression is most reproducible.