CCR1

Across TCGA patient cohorts, CCR1 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCR1-associated genes across cancer lineages are ERK2, MEK1, and MSH2. Each is linked with CCR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCR1-to-partner and partner-to-CCR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by CCR1-low versus CCR1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCR1→partner) and Y-score (partner→CCR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.254	+3.169	.003	.018	3	2
UCEC	MEK1 →	+0.406	+3.169	.013	.019	3	2
UCEC	MSH2 →	-0.432	-3.312	<.001	.010	3	2
UCEC	mTOR →	-0.192	-2.000	.008	.032	3	2
UCEC	PEA-15_pS116 →	+0.458	+2.459	.003	.019	3	2
UCEC	Cyclin-E1 →	+0.398	+3.000	.042	.036	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

ERK2 by CCR1 expression — UCEC

Explore this box plot interactively →