CCR1

Across TCGA cell cohorts, CCR1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCR1-associated genes across cancer lineages are GYS2, FAM24A, and SLC22A10. Each is linked with CCR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCR1-to-partner and partner-to-CCR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GYS2 grouped by CCR1-low versus CCR1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCR1→partner) and Y-score (partner→CCR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GYS2 →	+0.040	+3.930	<.001	.003	3	1
LARGE_INTESTINE	FAM24A →	+0.050	+4.437	<.001	.004	3	1
SKIN	SLC22A10 →	+0.172	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

GYS2 by CCR1 expression — LARGE_INTESTINE

Explore this box plot interactively →