CCPG1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CCPG1 mutation is significantly associated with the RNA expression of many other genes, with 470 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCPG1-associated genes across cancer lineages are GSG1L2, DPT, and CCDC195. Each is linked with CCPG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCPG1-to-partner and partner-to-CCPG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSG1L2 grouped by CCPG1-low versus CCPG1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCPG1→partner) and Y-score (partner→CCPG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaGSG1L2 →+0.034+4.384<.001.00632
BLOOD_LeukemiaDPT →+1.480+3.769<.001.00831
BLOOD_LeukemiaCCDC195 →+0.724+3.944.002.00631
LARGE_INTESTINEEIF3L →+0.574+3.257.001.00231
LARGE_INTESTINEFZD3 →+0.867+3.364<.001.00231
LARGE_INTESTINEIL7 →+0.949+3.451<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 470 associations by consensus.

GSG1L2 by CCPG1 expression — BLOOD_Leukemia

Box plot of GSG1L2 in CCPG1-low vs CCPG1-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration