CCP110

Across TCGA cell cohorts, CCP110 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CCP110-associated genes across cancer lineages are GPR101, SLC2A7, and DMRTB1. Each is linked with CCP110 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCP110-to-partner and partner-to-CCP110 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPR101 grouped by CCP110-low versus CCP110-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCP110→partner) and Y-score (partner→CCP110) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	GPR101 →	+0.070	+4.906	<.001	.006	3	1
OESOPHAGUS	SLC2A7 →	+0.016	+4.906	<.001	.006	3	1
SOFT_TISSUE	DMRTB1 →	+0.045	+4.417	<.001	.004	3	1
SOFT_TISSUE	REG3G →	+0.160	+4.222	<.001	.007	3	1
SOFT_TISSUE	TCHHL1 →	+0.031	+4.417	<.001	.004	3	1
SOFT_TISSUE	OR56A4 →	+0.012	+4.977	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

GPR101 by CCP110 expression — OESOPHAGUS

Explore this box plot interactively →