CCNYL6

Across TCGA pan-cancer cohorts, CCNYL6 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated CCNYL6 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CCNYL6 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CCNYL6 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LAML show a favorable association.

LUAD, UVM, and KICH are the cancer types where CCNYL6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.448	0.269	<.001	125	view →
UVM	DFS	Tertile	All	0.449	0.849	<.001	123	view →
KICH	DFS	Median	II,III,IV	0.548	0.921	.002	58	view →
LAML	DFS	Quartile	All	0.747	0.370	<.001	42	view →
LGG	OS	Tertile	All	0.313	0.639	<.001	24	view →
ACC	DFS	Median	All	0.551	0.764	.010	24	view →
BRCA	OS	Median	IV	0.904	0.646	.027	16	view →
THCA	DFS	Quartile	III,IV	0.876	1.000	.008	12	view →
LIHC	OS	Tertile	III,IV	0.378	0.695	.007	10	view →
READ	DFS	Tertile	IV	0.403	0.778	.011	9	view →
BLCA	DFS	Median	All	0.187	0.465	.017	8	view →
SARC	OS	Tertile	All	0.392	0.727	.004	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

CCNYL6–LUAD (DFS)

Open the LUAD breakdown →