CCNYL2

Across TCGA pan-cancer cohorts, CCNYL2 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of CCNYL2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CCNYL2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCNYL2 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

KIRC, HNSC, and THCA are the cancer types where CCNYL2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCNYL2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	+1.200	<.001	12	view →
HNSC	All	All	+0.256	.002	6	view →
THCA	All	III,IV	−0.022	.017	5	view →
LUSC	All	All	+0.360	<.001	4	view →
BLCA	All	All	+0.862	.012	2	view →
KICH	Female	All	−0.168	.005	2	view →
KIRP	Female	II,III,IV	−0.142	.011	2	view →
BRCA	All	III,IV	−0.086	<.001	2	view →
PRAD	All	All	−0.080	.002	2	view →
LUAD	Female	II,III,IV	−0.057	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

CCNYL2–KIRC

Open the KIRC breakdown →