CCNT2

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CCNT2 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CCNT2 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CCNT2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CCNT2 expression acts as an unfavorable survival marker, although some lineages such as UCEC and PDAC show a favorable association.

UCEC, PDAC, and GBM are the cancer types where CCNT2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECDFSMedianAll0.9370.779.0218view →
PDACDFSQuartileIII,IV0.8820.432.0344view →
GBMOSTertileAll0.4810.270.0334view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CCNT2–UCEC (DFS)

Kaplan–Meier survival curve for CCNT2 mass-spec protein-high vs -low samples in UCEC.

Open the UCEC breakdown →

Exploration