CCNT2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCNT2 mutation is significantly associated with the RNA expression of many other genes, with 3,742 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNT2-associated genes across cancer lineages are RN7SL134P, MFSD12, and TCOF1. Each is linked with CCNT2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCNT2-to-partner and partner-to-CCNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by CCNT2-low versus CCNT2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNT2→partner) and Y-score (partner→CCNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL134P →+0.091+1.763.001.00733
SKCMMFSD12 →+1.014+3.331.003.00533
SKCMTCOF1 →+0.480+3.719.003<.00133
UCECTCP11X3P →+0.174+1.714.001.00133
UCECRNA5SP411 →+1.020+2.213<.001<.00133
UCECRNA5SP412 →+0.396+1.829.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,742 associations by consensus.

RN7SL134P by CCNT2 expression — UCEC

Box plot of RN7SL134P in CCNT2-low vs CCNT2-high samples in UCEC.

Explore this box plot interactively →

Exploration