CCNT2

Across TCGA patient cohorts, CCNT2 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNT2-associated genes across cancer lineages are Caspase-7-cleavedD198, C-Raf, and PRDX1. Each is linked with CCNT2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCNT2-to-partner and partner-to-CCNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by CCNT2-low versus CCNT2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNT2→partner) and Y-score (partner→CCNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.425	+1.505	.032	.034	3	3
UCEC	C-Raf →	+0.125	+1.321	.009	.029	3	3
SKCM	PRDX1 →	+0.533	+3.000	<.001	.034	3	2
UCEC	MEK1 →	+0.310	+3.000	.011	<.001	3	2
UCEC	4E-BP1 →	+0.229	+1.584	.011	.009	3	2
SKCM	HER2 →	-0.367	-3.321	.012	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Caspase-7-cleavedD198 by CCNT2 expression — UCEC

Explore this box plot interactively →